Tumors of the prostate

Sarcoma of prostate cancer. Sarcomatosis prostate cancer is rare, mainly in childhood or adolescence. It grows rapidly, reaching sometimes enormous size. Sooner have difficulty with urination and defecation, anemia, cachexia.
By palpation in place of the prostate and above is determined by painful swelling smooth, thick consistency. With the growth of the tumor she softened in whole or in places simulating the abscess prostate. Patients die from cachexia and urosepsis. Metastases rare.
Forecast hopeless, symptomatic therapy, including the imposition if necessary suprapubic mahaputera fistula.
Prostate cancer. This disease is relatively common, accounting for 1.2 to 2% of all cancers in men.
Prostate cancer is possible at any age, but most often is observed after 40 years.
Unlike the so-called hypertrophy of the prostate, which is a adenoma periuretralnuu glands, cancer comes from the tissues of the prostate, most often from the peripheral areas adjacent to the capsule.
Prostate cancer that originates from its glandular epithelium, forms initially one or more dense nodes of the cartilage consistency, and the rest during the consistency and form of cancer remain normal.
Cancer infiltrate can capture and the entire gland grow its capsule and go to the surrounding tissues and organs. In such cases, the prostate is represented increased, bumpy, woody consistency, motionless, without a clear contours. Prostate cancer can develop in Central direction, squeezing and deforming the urethra and bladder neck like periuretralnuu adenomas, but there is a marked trend upward, toward the seed bubbles, which are often involved in the process. However, cancer infiltrate surrounds and squeezes the ureter, causing difficulty of urine outflow of them and expansion of the overlying departments of the ureter and renal pelvis with symptoms of kidney failure. Cancer sometimes invade the wall of the bladder, infiltrates the rectum. Extending fiber pelvis, prostate cancer is putting pressure on the nerve nodes and trunks, which is accompanied by severe pain in the pelvic area, radiating to the thigh, lumbar-lestrovoy region, in the crotch and rectum. The tumor early metastasizes, most often in the flat bones, the bones of the pelvic ring, sacral, lumbar vertebrae and the hip bone, less often in the lungs and lymph nodes. Bone metastases in patients with prostate cancer have mainly osteoblastami the nature and cause overgrowth of bone tissue, sometimes they have osteoclastami nature, leading to the destruction of the bone.
Another 70 years ago F. I. Sinitsyn said that castration causes atrophy prostate, and invited her for treatment of prostate tumors.
Currently experimentally proved that the hormone stimulates egg, and the female hormone inhibits the development of prostate cancer. Pieces of cancer of the prostate, is planted in front of the camera eye of the animal grow in males, but dissolve in females. However, they grow and females, if they enter the androgen. According to modern views leading role in the etiology of cancer of the prostate gland plays a hormonal imbalance.
In the initial period of the disease is asymptomatic or cause urination disorders, no different from those of prostate adenoma, i.e. fast and difficult urination with a peremptory craving. Often the only symptom is lumbosacral or ishialgia pain, depending on bone metastases or the pressure of the tumor on the nerve stems and roots. Sometimes the first clinical manifestation of the disease is a pathologic fracture at the site of metastasis. If the tumor presses against the lower segments of the ureters, there are a pain in the kidneys, and the acceding infection leads to pyelonephritis.
The disease usually progresses slowly, but sometimes quiet during her suddenly replaced by stormy metastasis or fast development of pyelonephritis or uraemia. Any persistent ishialgia in men older than 40 years and bone metastases and broken bones (often femur neck), caused by the inadequate reason, suspicious of prostate cancer.
Diagnosis in most cases not difficult. Even in the early cancers, the nodes available palpation per rectum. Isolated hilly sites or sections woody consistency, paraproctitis infiltrates very common and in most cases sufficient to establish a correct diagnosis. Typical tumor growth towards the seminal vesicles in the form of a bull horns.
For differential diagnosis with prostate adenoma known value has a cystoscopy. Prostate cancer bladder neck appears to be swollen, thickened, with blurred contours.
Chronic prostate cancer can be distinguished on the basis of the anamnesis and absence in the urine and the secret of the prostate cells, and from tuberculosis prostate - no-Mycobacterium tuberculosis.
Stones prostate palpation can give the same picture as cancer. The diagnosis revealed on the basis of x-ray.
If the differential diagnosis is still unclear, it is necessary to resort to biopsy a trocar, which are injected into the prostate through the perineum or rectum. Turn trocar of the prostate is cut out a piece of tissue for examination.