Orotic acid

Orotic acid (synonym vitamin B13)- derived pirimidina; 4-uracil-carboxylic acid. As a direct predecessor of pyrimidine bases (see), orotic acid is widely distributed in nature. Plays a significant role in protein metabolism, influencing the processes of anabolism; closely associated with vitamin B12. Indications: liver and biliary tract, chronic intoxication (except cirrhosis with ascites); atherosclerosis of coronary arteries and peripheral vascular I - III degree with symptoms of angina; myocardial infarction (orotic acid accelerates scarring); some forms of syphilis liver and stomach; some dermatoses, accompanied by disruption of the liver; anemia of different etiology; prematurity children and congenital galactosemia. Applied in the form of potassium salt (potassium orotate). Daily dose for adults: 1 to 1.5 g inside (but 0.5 g 2-3 times a day) for 20 to 40 days, with the observance of the dietary; children depending on age. Cm. also Vitamins.