Base material

Base material - gelatinous environment that fills the spaces between the cells and the connective tissue fibers. The base material is not identical intercellular substance, including, in addition to Acting century, all kinds of fibrous structures. At the submicroscopic level O. C. has the lamellar structure. On the border of contact connective and epithelial tissue O. century together with prisoners it retikuluma fiber forms a so-called basal membrane.
The basic substances are materials synthesized by connective tissue cells (fibroblasts, fat cells, endothelial), and also coming from the vascular bed.

      The components of the basic substance of the connective tissue
Of connective tissue cells | Mucopolysaccharides (hyaluronic acid, 
 | chondroitin sulfates And, In, With, 
 | heparin and other) 
 | Mucoproteins | 
 | Water | 
 | Enzymes | 
 | Immune | 
 | Metabolites | 
 Albumin | plasma 
 Globulins | 
 Vitamins | 
 Hormones | 
 Ions | 
 

The ratio specified in the scheme of the volatile components in physiological and pathological conditions.
The main substance involved in the transport of metabolites between cells and blood. This function is determined primarily by the properties of a high polymer protein and mycopolysaccharide complexes. The last form submicroscopic structure O. V. and function as a molecular sieve and exchangers. Thus, physiological permeability of vascular and connective tissue formations connected with the peculiarities of the structure of O. C.
Abnormal increase in the permeability of O. century, for example in the inflammatory processes, is the result of the action of enzymes - hyaluronidase as their own (tissue)and bacterial and plasma protease (cathepsins, plazmin). When C-vitamin deficiency the number of O. century increases, change the qualitative composition and physico-chemical properties. Introduction of ascorbic acid normalizes the basic substance. Cm. also connective tissue.