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Poisoning with alcohol substitutes and technical liquids

Wide implementation of chemistry in industry and everyday life has led to the emergence of a large number of products, referred to as technical liquids, some of which can be used with the purpose of intoxication. This kind of substitution of ethanol technical liquids, part of which belongs to the class of spirits, gave rise to a colourful picture of all kinds of poisoning, and have themselves technical liquids began to be called "surrogates" alcohol.
Methyl alcohol (methanol, wood alcohol, carbinol) is widely used in industry as a solvent. For color, smell and taste like alcohol. Poisoning them at present is relatively rare, this is mainly domestic poisoning, when the poison wrongly applied instead of ethyl alcohol inside. Occasionally, there are cases of mass poisoning on productions that use methyl alcohol as technical liquids.
Methyl alcohol is a strong neurovascular poison. Severe poisoning may occur after ingestion 7-10 ml Lethal dose varies from 30 to 100 ml and above. It should be noted in the individual sensitivity of the organism to methyl alcohol. Described cases of death after administration of 5 ml and recovery after consumption of 250-500 ml Persons who have had large doses of methyl alcohol, are often the source of false information about his "safety"than promote the use of it with the purpose of intoxication.
Methyl alcohol is rapidly absorbed from the gastrointestinal tract. It is oxidized in the body several times slower than ethyl alcohol. Special toxicity of methyl alcohol is associated with slow oxidation and toxic products of oxidation (formaldehyde, formic acid). Methyl alcohol in the blood after poisoning occurs within 3-4 days. About 60 % of the received dose is excreted in exhaled air, about 10 % from urine. The selection of his kidneys is approximately 3 days, formic acid - for 5-6 days.
For poisoning depends on the dose and sensitivity to the body. After taking the poison pretty quickly there comes a kind of euphoria, which is in contrast to alcohol intoxication is not accompanied by a pronounced arousal or elevated mood, and more like a hangover with a headache, weakness, incoordination, etc. This state quite quickly turns into a heavy sleep. After sleeping victims feel good. This latent period of imaginary well-being continues to 1 day. Then come the sudden malaise, dizziness, muscle weakness, pain in the lower back and abdomen. The victims in this period may fall into a state of strong excitation, or suddenly lose consciousness. There has been a sharp reduction of view, which in severe poisoning ends with blindness. Death usually occurs in a state of deep coma due to paralysis of the respiratory center. Without timely medical treatment death usually occurs on the third day. When recovery of the victims often remain persistent disorder of view up to blindness, functional inferiority of the liver, etc.
In the study of the corpse is usually defined pattern characteristic quickly actual death. Most long-methyl alcohol is in the cerebrospinal fluid - from 3 to 12 and even up to 45 days.