Transplantation front or back half of the body

Pages: 1 2 3 4 5

To use the internal organs with the least damage and to study their condition after transplantation, we were transplanted not only different complexes organs, but half of the dog's body. The first experiences have convinced us that to transplant the front or the back half of the body from a surgical point of view, it is much easier, than, for example, is a body such as the heart.
As we have said, the greatest technical difficulties when changing represents the connection of blood vessels and the location of the transplanted organ at the new location. When not good enough to stitch blood vessels blood in the place of vascular suture curtailed, leading to poor circulation and death transplanted organ. If it fails, its location inside the cavity may move, bend, pinching or twisting of the United vessels, which also results in the death of transplant.
More favorable conditions are created when we transplant the right half of the body of the dog (front or back). To do this, you need to make only two large blood vessel at the level of the diaphragm. When transplanting the rear side of the body all organs of the abdominal cavity remain intact and preserve the natural location. In addition, transplantation half of the body gives the opportunity to observe simultaneously for/by many state bodies.
Based on these premises, we made several attempts to join the front half of the body one dog with rear half to the other. To carry out this operation is not difficult, but when the spinal cord transection often there is a sharp fall in blood pressure, which at first did not allow to achieve long life of this body, composed of two halves. To address this concern we changed the form of experiment were transplanted half of one dog is not already to the other half, and to undamaged a dog. When transplanting the front half of the body puppy to a dog, and back - to another, we had the opportunity to study the status and activities of transplanted organs, largely retained the link with the nervous system. When transplanting the same individual organs nerves, of course, have to be cut.
Almost similar experiments were conducted in the following way. Was selected large puppy and two large dogs. Trunk puppy (under General anesthesia and artificial respiration) crossed in the middle part of the chest. The top half of the puppy's body, consisting of the head, the front legs and part of the chest, but with the remote heart and lungs, after preliminary staple vessels had moved to the neck free dogs. The rear half of the puppy, which included all the organs in the abdomen and lower limbs, got another adult dog (with the accession to the neck vessels or removed kidney).
Transplanting back half of the puppy's body was produced by us only in three cases. The life span of these halves reached 6 days. However, during this period we could see that the organs transplanted in the composition half of the body, are in better condition than the organs transplanted separately.
Previously, we had to leg transplant from one dog to another. We also observed the experiments of Professor P. N. Mazaeva and P. M. Chepova transplant legs of the dog. In these experiments, as a rule, already on 3-4 day after operation developed very pronounced edema transplanted legs, which had led to the loss of limbs. In contrast, in our experiments to transplant the lower half of the body, even on the sixth day after the operation, edema of the extremities not occurred.
A similar phenomenon was observed in respect of the kidneys. As already indicated, in separately transplanted kidneys had a severe inflammation. In the kidneys, transplanted together with the back half of the body, such inflammatory phenomena were revealed. These observations showed that during the transplantation of separate bodies should strive to preserve their physiological conditions.