Organochlorine compounds

Organochlorines Aldrin, dieldrin, DDT, HCH, heptachlor, polychlorine, lorinden, Horten, chlorfin and others; related to the nervous and parenchymatous poisons, many have irritant effect on the respiratory system. Expressed properties accumulation (storage), especially when exposed to heptachlor and floridana. The most toxic are DDT and hexachloran.
Acute poisoning. The clinical picture depends on the ways of getting poison dose or concentration. Latent period from several minutes to several hours.
When released into the digestive tract develop gastrointestinal disorders (nausea, vomiting, pain in epigastralna area and the right hypochondrium), sharp headaches and dizziness, General weakness, and in severe poisoning - shortness of breath, fever, staggering gait, convulsions, delirium, and coma. In the blood, leukocytosis, accelerated ROHE, anemia, hypocalcemia. The defeat of the liver and kidneys. Inhalation : irritation of mucous membranes of the upper respiratory tract and eyes (cough, shortness of breath, acute rhinitis, nasal bleeding, slezotechenie), and in some cases, pulmonary edema.
By ingestion of large quantities of poison on the skin develop skin lesions (reddening of skin, dermatitis) in combination with General toxic manifestations.
Chronic poisoning. Dominated by changes in the nervous system (neurasthenia, polyneuritis, encephalomyelopathy) in combination with the human liver, kidneys, gastrointestinal tract, cardiovascular system and respiratory organs. Frequent diseases of the skin allergic nature.
First aid and treatment. In acute poisoning - the immediate cessation of contact with the venom. After contact with the poison in the gastrointestinal tract - profuse gastric lavage with a 2% solution of sodium bicarbonate, warm water with a suspension of activated charcoal (30 g/l), followed by the appointment of salt laxatives, activated carbon, intravenous glucose with vitamin B1 and ascorbic acid, gluconate calcium, soothing, heart funds. When respiratory depression - lobeline, quote, artificial respiration, oxygen. In severe acute poisoning - re bloodletting with the subsequent introduction of an isotonic solution of sodium chloride glucose (800 ml izotoniceski solution of sodium chloride - 200 ml of 2% glucose solution). In case of contact with eyes rinse with 2% solution of sodium bicarbonate or izotoniceski solution of sodium chloride. After contact with skin wash contaminated with poison places with soap and water. Contraindications: adrenaline, morphine, chlorine-containing drugs, fats, alcohol.
In chronic poisoning shown tonic and symptomatic therapy: glucose, ascorbic acid, vitamin B1 insulin, calcium gluconate, barbiturates, a small dose of bromide, Valerian. Diet mainly dairy and vegetable that is rich in vitamins, lesion of the liver - the cheese, the fat restriction, lipokain.