Pinos (from the Greek. pyknosis - seal) - the process of degeneration of the kernel, resulting in cell death. Pikes usually accompanied by shrinkage of the nucleus of the cell (see), the disappearance of its structural parts and strengthening of basophilia, what is connected with increase in quantity of DNA, and with the seal of the nuclear substance. Sometimes the chromatin perishing core breaks up into a large number of spherical cells (kariorexis), which later degenerate. Pikes observed in aging cells, various pathological processes, viral infections, the effects of poisons, malignant tissue growth, the action of ionizing radiation and other