Poikiloderma - a special type of skin atrophy. On very thin, resembling a crumpled tissue paper slightly shiny skin seen numerous brownish-yellow (hyperpigmented) and light (depigmented) spots and numerous telangiectasia (see), in the total aggregate giving the skin a kind of mottled appearance, with lace or net pattern (net poikiloderma).
Poikiloderma may be congenital, is revealed in the first years of life, often combined with other signs of congenital malnutrition (stunting, anomalies of the teeth, nails, congenital cataract and other). Acquired poikiloderma occurs with prolonged skin exposure machine oil, resin, tar, some cosmetics, thermal and radiation factors (often does the skin of the face, neck, upper chest). Cause of acquired poykilodermii can be also some diseases - dermatomyositis, Hodgkin's disease, leukemia, mushroom avium, patchy and lichenoides parapsoriasis, scleroderma, endocrine disorders and other lesions of the skin is often symmetrical, sometimes there is a gentle pityriasis peeling, itching often missing. The course of chronic.
The treatment is ineffective, mainly comes down to identifying and addressing external causes and disease-causing poikiloderma. Inside appoint vitamins a, E, PP, ascorbic acid. In order to prevent, avoid mechanical stimulation, hypothermia, overheating is especially dry, more prone trophic disorders of the skin.

Poikiloderma (from the Greek. poikilos - and-white, spotty and derma - skin - the skin condition where available simultaneously atrophy, pigmentation and telangiectasias are sitewide, give the affected area of skin mottled appearance. Poikiloderma belongs to the group of atrophic skin diseases. P. occur in both men and women, in early childhood and in old age; they may be congenital or acquired, common and limited. P. may be accompanied by diseases of the muscles (see Poikilodermatomyositis), there are sometimes simultaneously with scleroderma (scleroprotein), as well as mushroom avium, Hodgkin's disease, leukemia, lupus. Poikilodermatous changes in the skin can develop by devolution, red flat denying.
The most frequently observed following clinical forms of P. 1. Vascular atrophic poikiloderma Jacobi (poikilodermia atrophicans vascularis E. Jacobi), previously considered as an independent disease, currently described as one of the stages in the dynamics parapsoriasis, mushroom avium, Hodgkin's disease. In addition to atrophy, pigmentations and telangiectasia, P. meet capillary hemorrhage, Petriashvili peeling and miliary knots. When P. may experience blurred expressed swelling of the face and extremities, joint pain, malaise. Histologically-atrophy of the epidermis, the increase of pigment in the basal layer, perivascular, mostly round-cell, infiltrates in the upper part of the dermis, the atrophy elastic fabric. Differential diagnostics is carried out with scleroderma, rentgenoterapii, pellagra, some medical dermatitis (mainly medications gold, arsenic).
2. Net pigment poikiloderma face and neck, described by Civetta (poikilodermia reticularis retinitis faciei et A. colli Civatte). This form P. clinically and histologically is identified with toxic melanosis Riehl; more (clinic and treatment) - see melasma. Sometimes poikiloderma Civatte occurs as a result of professional and household intoxication.
3. Poikiloderma Thomson refers to the innate atomization, is rare, starts from the first weeks of life redness and some swelling of the skin on the cheeks and buttocks, and then groin and armpit areas, which receive the light atrophy, pigmentation and telangiectasia; can meet bone degeneration. Rothmund (A. Rothmund) described these changes simultaneously with juvenile cataracts (see Rotunda syndrome).
4. Localized poykilodermii - secondary skin changes, emerging as a result of various radiation (x-ray, ultraviolet irradiation, insolation).
In order to prevent P. avoid various injuries, cooling, infections, occupational hazards. Therapy is ineffective and largely confined to treating the disease, in which P. is just one of the symptoms. Recommend various corticosteroids and multivitamins.