Prednisolone

Prednisolone (Prednisolonum) is a synthetic corticosteroid drug with glucocorticoid properties. The nature of the actions similar to cortisone (see), but in 3 to 5 times more active. Indications for use are the same as for cortisone. In addition, prednisolone is used topically for skin diseases (eczema, itching, dermatitis and other) in the form of ointment, and intramuscular and intravenous in urgent cases (shock, bronchial asthma) as hydrochloride prednisolone 15 - 30 mg Daily dose P. when the articular rheumatism 0,02-0,05 g Finished treatment, gradually reducing the dose. Method of production prednisolone: tablets to 0,005 g; ml to 1 ml containing 30 mg of the hydrochloride prednisolone; prednizolonovuyu ointment (5 g ointment in tubes containing 25 mg of prednisolone).

Prednisolone (Prednisolonum; synonym Delta-Cortef, Di-Adreson-F, Ultracorten-H) is a synthetic corticosteroid drug with glucocorticoid properties; digidrirovanny similar hydrocortisone Delta'degidrogidrokortizon. On therapeutic activity 4 times that of hydrocortisone (see). Used as anti-inflammatory and antiallergic means. Shown for rheumatism, gout, infectious and psoriatic arthritis, rheumatic heart disease, endocarditis, leukemia, acute nephritis, acute and chronic thyroiditis, bladderwort, keratitis, atopic dermatitis, bronchial asthma and other allergic diseases. Dose at the beginning of treatment is 20-40 mg, then gradually diminish to 10-5 mg taken orally in two or three doses during the day. Doses are individuated taking into account the nature of the disease, tolerance and therapeutic effect. P. contraindicated in acute infectious diseases, diabetes, pregnancy, ulcers of the stomach and intestines. Side effects: hyperglycemia, glycosuria, swelling, menstrual irregularities. To prevent side effects simultaneously appoint anabolic steroid drugs (see). After a long course of treatment with prednisolone and its application of high doses may cause symptoms gipokortitizma due to temporary oppression of napochechnikov crust. To prevent this course of treatment is complete, gradually reducing the dose of prednisolone and applying injections of adrenocorticotropic hormone (see) by 10 UNITS, 2 times per day during 2-4 days. The form of release: tablets 5 mg. Cm. Hormonal drugs.