The prestige of the nephron

Pages: 1 2 3 4 5 6 7 8

But while in the technological lines of the turn will come to the collecting tubules, nephron still have to work hard, to produce particularly subtle, complex operations.
Because kidney - tool homeostasis, the nephrons not forget that the internal environment of the body and stable, and variable. Sustainability her wavering. And it is necessary to hesitate to immediately rectify.
Suppose, from the depths of the body goes signal: water supplies become scarcer, the concentration of electrolytes increases. Central nervous system sends this information to its hypothalamic region. With the specific goal to encourage the production of the hormone that blood will be delivered to the kidneys as a security officer. In the peripheral Department of nephron it sets, albeit briefly, his orders: complicates the original work of the tubule cells - the reabsorption, return to the blood of sodium. Loss of its increase, and at the moment it is good for the body. Hormone activates the enzyme that dissolves protein mounting between the tubule cells. Through the open gateways water can easily leaked and then gets into the plasma, restoring its volume. Of course, decreases the amount excreted by the kidneys liquid - diuresis. Therefore, a hormone called vasopressin - ADH.
Option two: sentinel of the Central nervous system report the excess fluid and the decrease in the osmotic pressure. The task of nephrons clear: to strengthen the excretion of water, to increase the return of sodium. In this case the Central nervous system harvested another channel management kidneys. Order activated receives not the hypothalamus (ADH now not necessary, may increase diureza), as close neighbors of the kidneys, adrenal glands. Requires additional portions of their products - the hormone aldosterone. Through intermediaries he can make cells canaliculi energetically to reabsorbiruetsa in blood sodium, the main force of osmotic pressure.
Both hormones and antidiuretic, and aldosterone,which finally establish the balance of sodium and water, are working with the following after Genle hinges Department canaliculi. Here are concentrated devices for dosing of acid and alkaline foods - what and how many to remove at the moment, how much to put in the blood alkaline compounds, how many create their advanced from scrap semi-finished products. Tape of this program can scroll in both directions, the nephron removes - on demand - and alkaline and acidic components, more often the latter.
Cells of this Department canaliculi able to migrate from the blood into his bed of hydrogen ions. And the crowd out there sodium from the waste compounds. He is free to return to the blood, but not in and of itself, and giving life to the molecules of bicarbonate - the most valuable buffer systems. And hydrogen ions, fighting with sodium, lose freedom and free the body from its presence, standing out as part of acids and acid salts. This is to maintain normal alkalescent reaction plasma. If these efforts are not enough, for more effective to reduce the acidity of the nephron includes technological chain own reserves: using enzymes synthesizes for neutralization of acids with ammonia. And a lot of 0.6-0.7 grams per day. In the tubule he turns on hydrogen ions. Should multiple razmalyvanie biochemical figures, during which the sodium gets the opportunity to form bicarbonate, recharge alkaline reserve of blood. Here are a complex of building and rebuilding produces tubule in his Department, which, in essence, crowns the work of kidneys for the sake of maintaining the stability of the structure and properties of blood plasma.
The design capacity natronnoy biochemistry pose large internal reserves. Their Foundation is the consistent inclusion processes-antagonists and parallel processes-doubles.