Impurities in cow's milk

Adverse reactions to cow's milk in some cases not due to the constituent elements of the milk, and its impurities. These impurities can get into the milk in various ways, for example, from the blood in the breast, as a result of injections or tumbled into the udder, pomeshivanii or milk contamination during transport or processing.
In raw cow's milk impurities found the following potential allergens: penicillin, wheat, ground nut, flax seed, seed cotton, ragweed, primrose true and bacteria [43]. Milk also can meet DDT, as a rule, insignificant quantities [44]. In some homogenized samples of condensed milk and milk mixtures were determined rather high concentrations of lead [45].
In the past frequently mixed in milk were antibiotics. The fact that mastitis in cows were treated with penicillin, entering it in the mammary gland, or, more rarely, other antibiotics, such as streptomycin or drugs tetratziklinovogo stimulants. In the early 50-ies in the United States was held on 3 studies of marketed milk [46]. Penicillin was discovered in the 3.2 11.6% of samples tested and the concentration varied from 0.003 to 0.55 U/ml, bacitracin - 1% of the samples, and streptomycin is only one of 1706 samples. While streptomycin and oxytetracycline are not active antigens oral introduction, penicillin is known as a strong allergen, and even a tiny amount of it can cause sharp reactions in people sensitive to penicillin. To prevent such risk Management on sanitary inspection behind quality of foodstuff and medicines of the USA demanded in 1953 from the manufacturers of antibiotics for the treatment of mastitis in cows, invest in each package medication warning that milk from diseased cows can be used for food no earlier than 3 days after stopping treatment with antibiotics.
Wicher et al. [51] for example sensitive to penicillin woman, who has developed a sudden allergic reaction after taking milk, containing about 10 IU/ml penicillin.
The literature describes a case of unintentional introduction of 100 ml pasteurized milk in the vein of a patient suffering from duodenal ulcer [52]. The patient within 10 min developed a systemic phenomenon immediate hypersensitivity type, including urticaria. Whether these symptoms IgE mediated hypersensitive reaction or other mechanism has not been established. After the illness the consumption of milk was not accompanied by any symptoms.