Allergy to cow's milk, as a rule, will result in full recovery excluding this product from the diet. Often, however, the process involved, and other allergens, so until then, it is still impossible to identify them and to exclude, complete recovery occurs. During examination 59 sensitised to milk children Gerrard et al. [1] found that 20% of them noted also allergic to oranges, 20% -to the soya, a 12% for eggs, 8% - to wheat, 7% - to tomatoes, 7% - to rice, 5% - to the pork, 5% - to the lamb and 5% for barley.
The duration of allergies to milk varies widely in different patients and partially depends on the age. The duration of the disease in children under 2 years can be determined more likely than adults or older children. Survey [1-4] children under 2 years of age and older show that allergies to milk, usually fades in a few months and in many cases completely disappears or becomes much less pronounced for 1-2-th years of life. The maturation of the gastrointestinal tract, the formation of local secretory IgA antibodies and other immune system components contribute to the formation of protective mechanisms aimed at the utilization of foreign proteins and prevent the development of sensitization to them. Note, however, that the maturation of the gastrointestinal tract is not a critical factor; sensitivity to milk can be saved in adolescence and adult people; in addition, sometimes the disease develops in the period when the formation and maturation of the gastrointestinal tract has been completed.
Control tests of children with allergies to milk from the first months of life, show that by the end of the 1st year 17-65% of them [1, 2] are able to tolerate milk in some form or another. The severity of the symptoms, apparently, does not affect the prognosis of the disease [1]. If sensitization to milk is stored for a long time, in a process involving new shock bodies or develop new symptoms after the disappearance of old ones. In one of the papers [5], it was found that allergic to milk flows easier and faster in children, originally at breastfeeding, as well as those, which sooner was diagnosed with the disease and introduced a milk-free diet.
The main purpose is the strict observance of milk-free diet, during which at regular intervals in 6-18 months, spend samples of milk, which gives the opportunity to determine the time to reduce the sensitivity to subclinical level. Complete elimination of milk during the first 6-18 months after diagnosis, it is advisable not only to achieve and maintain an asymptomatic condition of the patient, but for the long-term prognosis. A number of authors [6-8] described the histology and immunological changes of the intestinal mucosa, which developed after receiving such quantity of milk that did not cause the onset of clinical symptoms. These data are important to consider when treating sensitive to milk persons who do not have (or develop poorly) symptoms in response to the intake of small amounts of milk or dairy products, and anamnestic data indicate caused by the intake of milk gastroenteropatii and malabsorption. Long-lasting defeat mucous membrane of the intestines, apparently, increase the period of increased sensitivity to milk and lead to hidden violations of the digestive process. They probably also contribute to the development of the hypersensitivity reactions to other allergens and the emergence of other types of allergic diseases. In persons with suspected bowel disease caused by the intake of milk, bowel biopsy should be performed before and after samples of milk. In case of positive results of the test, the patient requires especially careful follow-up, because such a patient receiving milk can have a subtle impact for many years or even the whole life.
Even with the disappearance of the symptoms of hypersensitivity to milk many patients remain prone to allergies. Relapse or development of sensitization to other allergens phenomena rather characteristic; new symptoms may be similar to the old or fairly differ from them. If Allergy symptoms develop in a patient previously suffered from milk intolerance, the doctor must remember that this product is undoubtedly plays a role in the symptoms of the disease, even if at first glance the patient tolerates the milk, and allergic status seems little associated with previous allergic to milk. In such cases it is recommended again to exclude milk from the diet; this measure can be very effective for the treatment of a new kind of Allergy.
Therefore, in each case, allergic diseases need to figure out has there been previously patient with allergic reactions to food, in particular, to cow's milk. If such a reaction in the past took place, one has to resort to the exclusion of this or that food for a certain period (usually 1 month) with further tests to confirm or exclude the diagnosis of allergies to this product.