Anti-inflammatory therapy

Anti-inflammatory therapy in rheumatoid arthritis is one of the most important links actually pathogenetic therapy aimed at preventing the development and further progression of valvular heart disease, myocardiosclerosis, obliteration of the pericardium, secondary changes in other affected rheumatism bodies.
To the means of anti-inflammatory action, currently used for the treatment of active phase of rheumatoid arthritis include steroid hormones, salicylic, pyrazolone, indole derivatives, derivatives of phenylacetic acid and other Mechanism of action of these diverse in its chemical structure of substances is different, so they are isolated or combined application requires not only a thorough preliminary analysis of the clinical features of disease, but also the acquaintance of the doctor with the main pharmacological characteristics and side effects of these drugs.
In brief the mechanism of action of anti-inflammatory activity of a number of drugs can be represented as follows: 1) the stabilization of lysosomal membranes; 2) the separation of oxidative phosphorylation and limitation thereby energy security inflammation; 3) inhibition of proteolytic activity; 4) the inhibition of proliferation of cellular elements in inflammation; 5) the effect on the metabolism of mucopolysaccharides and collagen proteins and other

  • Glucocorticosteroids
  • Salicylic acid derivatives
  • Pyrazolone derivatives
  • Indometacin
  • Voltaren
  • Ibuprofen
  • Immunosuppressive therapy