Pustular bacteria

Pustular bacteria (synonym pustules Palmar-plantar - a chronic relapsing skin of the palms and soles of unknown etiology. Assume that the disease allergic nature and is connected with the focal infectious foci (tonsillitis, carious teeth, and others). Pustular bacteria observed in age from 20 to 50 years.
pustular bacteriaskin Lesion begins in the center of the hand or foot arch and characterized by small, the size of a pinhead pustules, podzikowski with the reversion of crusts. Content of fresh sterile pustules. The skin in these areas has a pink color and covered with small scales. The eruption of pimples is pristupoobrazna, simultaneously on all affected areas, which gradually increase in size, and in a few weeks defeat is distributed symmetrically on both palms or soles. The disease lasts for years, compounded, then fell silent. Subjectively - itching and pain.
Treatment. The identification and remediation of focal infection leads to recovery pustular bacteria. Temporary improvement can give steroid hormones (by prescription). Naruzhno - emollient lotions and ointments.

Pustular bacteria [synonym: pustulosis palmaris et plantaris (Lever), acrodermatitis pustulosa (Rothstein)] is a chronic, relapsing pustular skin of the palms and soles, described by Andrews (G. S. Andrews). Described By Barber (N. W. Barber) psoriasis pustulosa palmaris et plantaris apparently identical pustular bakteriju Andrews and is not a form of psoriasis, pustular form which generally cause doubt.
The etiology and pathogenesis pustular bacteria unknown. Content of fresh sterile pustules. Andrews links skin lesion with focal infectious foci (tonsillitis, carious teeth) and considers a skin lesion as allergic reaction to hematogenous spread of germs, their decay products or toxins (similar tuberculinum, michigam and others). This view is confirmed by the fact that the destruction of focal lesions leads to healing skin lesions.
Histologically in the epidermis under the Horny layer is detected single chamber cavity filled with blood, a small number of lymphocytes and separate degenerated cells subulate layer. The bottom of the cavity does not reach the basal layer, separated from it by 1-2 rows subulate cells. Tangential diameter her more vertical. In the epithelial cells surrounding the cavity, little is marked intra - and intercellular edema. In the dermis moderate inflammatory infiltrate of lymphocytes, histiocytes and neutrophils, which are located around blood vessels. The mechanism of formation of pustules unclear. Most likely, the process begins with education focal spongiosa with the subsequent migration of white blood cells, destroying cells thorn layer.
Pustular bacteria occurs with equal frequency in men and women aged 20-50 years. The disease usually begins in the center of the hand or foot arch is often symmetrical, rarely with your fingertips, and in the coming weeks affects both palms and soles. Skin lesion is characterized by an eruption of small, the size of a pinhead, bubbles, the content of which is quickly becoming known. Pustules not rise above the level of the skin and consistently dry up with the reversion of a brownish color of crusts. Gradually the skin at the affected area is painted in pink or red color and a small plate covered with scales, between which the formation of new pimples. The eruption of pimples is pristupoobrazna, simultaneously on all affected areas. Lesions are slowly increasing by peripheral growth and can spread over the entire surface of the palms and soles. When localization at your finger tips, the process moves on to the nail bed, deforms and detaches the nail plate. Subjective pain and itching, increased in the period of exacerbation. The disease is chronic, over the years, compounded, then fell silent, and with rare exceptions cannot heal. The General condition is not disturbed.
Pustular bacteria different from disgestrotical defeats the absence of large bubbles type cooked sagas grains, acrodermatitis continua - pronounced symmetry, relatively rare defeat fingertips, a fraction of pustules, and histologically - absence spongiidae pustules Cogoa.
Treatment. Best action has reorganization of focal lesions. Temporary improvement can be achieved by the appointment of corticosteroids in combination with antibiotics. The external - in the period of exacerbation softening ointments and creams or drying wet bandages. During remissions - careful use of allow tools (tar, drug DCA) in the form of pastes, or ointments.