The distribution of alcohol in the body

The absorption of alcohol begins directly in the mouth, although most exposed to alcohol absorption in the gastrointestinal tract. It is carried out by diffusion, and fast. After a few minutes alcohol can be defined in the blood. Fluctuations of his concentration is very wide (up to 600 mg%). Dynamics concentration is as follows: first, the alcohol content is growing rapidly, and then decreases relatively slowly. It is shown that the decline is slower than the more alcohol got into the body.
The decrease in the concentration of alcohol in the blood is provided by two processes: the elimination of alcohol from the body and its oxidation. The total decrease in the concentration of alcohol in the body for an hour indicated by the value β60 and changes in per mil (PPT). It is established that the individual value β60 varies from 0,100 to 0.16%, which in terms corresponds to oxidation an hour in the body from 5.0 to 12.0 absolute alcohol (Shirinsky, Tomilin, 1983). Growth is possible with the use of significant quantities of alcohol, and to include compensatory ways oxidation of alcohol.
The maximum concentration of alcohol in blood is registered in 30 to 60 minutes after taking alcohol. The rate of increase of concentration of alcohol in the blood and the concentration values depend on a number of factors: individual biochemical characteristics of the organism, the degree of its "fitness" in the processing of alcohol, nature, food, quantities and concentrations of alcohol and other
About 90% of alcohol when ingested is oxidized, 5-10% out of the body, bypassing the dissimilation of the urine, breath, and then faeces.
Alcohol is metabolized (i.e. consistently oxidized) main (80-90%) in the liver, and is able to "download" it for 3/4 of all its oxidation capacity (Uspensky, 1984). The highest concentration of ethanol is registered in the liver, kidneys, lungs, salivary glands and testes.
It is very important that at relatively low concentrations of alcohol in the blood (of 0.2%) a person has detected a violation of the functions of the blood-brain barrier - a system designed to protect the brain from the effects of various toxic products. The penetration of alcohol in the brain provides its toxic effect on the Central nervous system (CNS). The maximum concentration of alcohol is detected in the cerebral cortex, but it is high enough in his other departments. The reason for the different distribution of alcohol in the brain still remains unclear.
Taken inside the alcohol is absorbed mainly in the small intestine (80%) and stomach (20%). In the stomach, it can stay without further processing within 3 h after administration with food. On the absorption of alcohol and its concentration in the blood is influenced by a number of factors, first of all, the nature of food intake. Products such as potatoes, meat, fats, prevent the absorption of alcohol in the stomach. It is important that the absorption rate is also dependent on the functional state of gastrointestinal tract. It is known that people with ulcers and gastritis absorption rate is significantly higher than in healthy people. This leads to a very sharp increase of concentration of alcohol in the blood after consumption. It is established that among persons who abuse alcohol, the rate of absorption is also higher. In addition, the rate of absorption increases at higher concentrations of alcohol consumed.
The duration of the phase of absorption of alcohol 40 - 80 minutes the maximum concentration of alcohol in the blood is detected in about 40-50 minutes, and then it decreases. After almost all the alcohol (98%) absorbed from the gastrointestinal tract, there is a phase of elimination (the selection of alcohol). Rate of elimination due to individual differences may vary in healthy 3-4 times.
So alcohol is already integrated into the human body. How the body tries to defuse got in it from the outside stuff?