Rat rickettsiosis

Rat rickettsiosis (synonym: rat typhus, endemic typhus) is an acute febrile illness of people, similar clinical manifestations with typhus (see). Rat rickettsiosis refers to the ricketsiosis group of typhus and occurs sporadically in places where widespread rickettsiosis rats and mice.
Etiology. Exciter rat ricketsiosis - rickettsiae a Moser (Rickettsia mooseri) - is a variant of rickettsiae of Prowazeki and close to them immunologic. Rickettsiae a Moser isolated from the blood of sick people, from the brain of the infected rats and mice, as well as from intestinal parasitic fleas, where they remain for life, standing out in large numbers with faeces. In the salivary glands fleas rickettsiae are missing, so the rat rickettsiosis through flea bites is not transmitted.
Epidemiology. For infection of a person mouse-rickettsiosis rather insignificant share of infectious waste fleas. Infection occurs when hit "fecal virus" on the damaged skin when the scratching and the wound from the bite of fleas and visible mucous membranes. The dispersion of the pathogen rat ricketsiosis happens with the urine of infected rodents, therefore, possible contamination and through foodinfected with the urine of patients rats. Rat rickettsiosis is more common during the autumn and winter months.
Disease from a sick person to a healthy is not transmitted.
Increasingly ill workers grocery stores and shops (the"disease of shopkeepers"), food enterprises and households.
The clinical picture. The incubation period of 8 to 12 days. The disease occurs acutely with chills, headache, body aches. 5-7-th day from the beginning of the disease on the trunk, limbs, sometimes on the palms and soles appears rash. Febrile period lasts on average about two weeks. Complications are rare. The Outlook is favorable, the restoration of ability to work fast. After the disease remains immunity. There are a disease only on the prevalence of antibody titers to the antigen rickettsiae a Moser over titers of antibodies to the antigen rickettsiae of Prowazeki in reactions agglutination and of complement fixation. Pathogenesis and pathology due to the rarity of deaths are not investigated.
Treatment. Patients mouse-rickettsiosis hospitalized to the infectious Department. Care and treatment are the same as with typhus. Assign biomitsin and terramycin fractional dose of 1-2 grams per day.
Basic preventive measures are reduced to the systematic extermination of rats and mice in the centers rat ricketsiosis and to prevent importation of infected rats in ports from arriving ships (deratization vessels, excluding transition rats on the territory of the port).
Along with this, measures should be taken to protect food products from rodents.
In the hearth diseases produce deratization (see) and disinsection (see). Specific prevention is not developed.