Reserpine

Reserpine (Reserpinum; synonym: Rausedyl, Serpasil) - gipotenzivee and neuroleptic agent, alkaloid rauwolfia (see). Applied for the treatment of hypertension. Assign inwards after eating, beginning of 0.0001-0.0003 g per day. Gipotenzivny effect develops gradually; if no effect dose gradually increased up to 0,001-0,002 g / day; on reaching effect daily dose also gradually reduced to 0,0005 - 0.0001 g; treatment with small doses over several months. Reserpine is also used in hyperthyroidism.
In psychiatry reserpine used in the treatment of diseases involving psychomotor agitation.
Higher doses inside: single - 0.002 g; daily - 0,01 g Side effects: weakness, dizziness, stomach pain, nausea, vomiting, diarrhea, bradycardia; with long-term use may phenomenon of Parkinson's disease, depression. Contraindicated in severe organic heart disease events decompensation and expressed aetiology, when nephrosclerosis, cerebral sclerosis, ulcerative disease of the stomach and duodenum. Method of production: powder (list a); tablets (list B) to 0.0001 and 0,00025 g Cm. also Antihypertensive drugs, Neuroleptics, Sympatholytic funds.

Reserpine (Reserpinum; synonym: Crystoserpin, Raunorin, Rausedyl, Resercen, Serfin, Serpasil, Serpin; list A) - alkaloid extracted from plant tissue; ester methyl ester rezerpinom and 3, 4, 5-trimethoxybenzoic Noi acids. Has a calming effect on the Central nervous system and hypotensive action. Prescribed for hypertension and some mental illnesses. Contraindicated in heavy losses of organic cardiovascular system events decompensation, cerebral sclerosis, nephrosclerosis, ulcers stomach and duodenal ulcer. Hypertension treatment rezerpinom start with small doses (0.1-0.3 mg / day), then increase to 0.5-1 mg a day. The treatment dose continue for several weeks. Mentally ill reserpine in large doses (0.5 - 5 mg / day). Side effects overdose or hypersensitivity: weakness, dizziness, somnolence, bradycardia, urticaria, nausea, vomiting, stomach pain. Release R. table. 0.1 and 0.25 mg. store in a sealed container in a dark place.
Cm. also antihypertensives, Sympatholytic funds.