Retikulez

Retikulez forms of leukemia characterized by a progressive expansion of the reticular cells, blood-forming organs.
The etiology of reticulata, like that of other leukemias, is not clear. The location of the reticular cells in the form of syncytium (and not in the form of free cells) not facilitate their transition into the blood, resulting in reticulata blood picture can be leikemicakie, and the number reticular cells in punctata bone marrow relatively small.
The clinical course there are acute, subacute and chronic forms of retikuleze. Acute forms occur with high fever, sometimes with an enlarged liver, spleen, or lymph nodes. Blood picture looks like the picture in aplastic anemia (see). In blood prevail lymphocytes, sometimes there is a shift hemogramme left, until immature and undifferentiated forms.
In punctata bone marrow, spleen and lymph nodes detect a different number reticular cells, sometimes in the form of a giant multi-core.
Subacute or chronic retikulez often occur with severe anemia, multiple tumor growths in organs and tissues, skin lesions.
For retikuleze severe, acute forms of the disease death may occur within a few weeks or months.

retikulez skin
Fig. 1 - 3. Retikulez skin. Fig. 1. The spotted form. Fig. 2 and 3. Erythrodermic form.
reticulosis
Fig. 1 - 4. Retikulez skin. Fig. 1 and 4. Nodular-nodular form. Fig. 2. Nodular form. Fig. 3. Eritematos nodular form.

Treatment. Patients with acute and subacute forms to be treated in the therapeutic or specialized hospitals. Used primarily steroids (prednisolone, triamcinolone), means cytotoxic activity (drugs that suppress the production of abnormal cells: cyclophosphamide, 6-mercaptopurine, and so on), and anemia - a blood transfusion, if secondary infection - antibiotics. The chronic course designate restorative treatment, and corticosteroids and cytotoxic drugs when indicated on the instruction of specialists.

reticular cells
Fig. 1. Bone marrow vertebra; reticular cells are interconnected processes. Fig. 2. Imprint bone marrow vertebra; reticular cells with nuclei of different shapes. Fig. 3 and 4. Proliferation reticular cells between the lobes of the liver (Fig. 3 - a small increase; Fig. 4 - big increase). Fig. 5 and 6. Tissue lymph node swept reticular cells (Fig. 5 - a small increase; Fig. 6 - a big increase).