Sarcoidosis

Sarcoidosis (synonym: disease Besnier - Beck - Saumane, benign chlamydia, Soumana) is a systemic disease that affects different organs and systems and greatly varying clinical manifestations. Leading clinical symptom no. Postmortem the basis of sarcoidosis is the so-called sarcodina granuloma resembling tuberculosis tubercle. It consists of epithelioid cells mixed with lymphoid elements and single giant cells, however, unlike tuberculosis, caseous necrosis is never. Etiology has not been studied, the majority of authors considers that sarcoidosis is not associated with tuberculosis infection and is an independent disease, belonging to the group of retikuleze. Sick people mostly young and middle aged.

sarcoid Beck
Fig. 1. SKD and miloslava forms of sarcoid Beck. The defeat of the lower lip.

Skin lesions occur in about half of patients with sarcoidosis, as a rule, they are not accompanied by itching, pain, or other subjective feelings.
The most common form of skin lesions - sarcoid Beck, which occurs in three basic varieties: 1) krupnouzlovoj - one or more sharply delimited nodes hemispherical shape size of 2 - 3 cm in diameter, initially rose-red color, then with brownish tint, not izyaslau; 2) melkozerova - multiple small scattered knots; 3) the most rare diffuse inflammatory variant slightly bordered infiltrates brownish-purple color; this species is close another form of skin sarcodon - the so-called ozloblennaya lupus (see Lupus pernio).
When sarcoidosis often found non-specific skin lesions, most often - erythema nodosum (see Erythema nodosum).
Different forms of sarcodon skin can occur simultaneously in one patient. Often reveal moderately increased peripheral limp. the nodes.
Lung and intrathoracic lymph nodes are the most frequent symptoms of the disease may develop acute, moderate fever, sometimes with nodular lesions of erythema or indirectly, accompanied by General weakness, malaise, joint pain, low grade fever, rarely fever wrong type, resembling the picture of the flu. Clinical manifestations manoharachary and hold different times, often disappearing without treatment within a few weeks, or may be completely absent.
Pulmonary manifestations of sarcoidosis reveal almost exclusively chest x-ray. When poor clinical manifestations on the radiograph find a distinct change. Often one and the same patient encounter different stages: 1) sarcoidosis stage I - increase and compaction intrathoracic lymph nodes, especially the root group, usually bilateral, although asymmetrical, reminiscent of chlamydia and TB bronchogenic; 2) sarcoidosis stage II - net infiltration basal areas of the lung, small, rupnieciba and disseminated forms of destruction of lung tissue resembling hematogenous disseminated tuberculosis; 3) sarcoidosis stage III - pneumosclerosis is rare.
Sarcoidosis can hit: 1) eye - subacute bilateral defeat of the iris and ciliary body (see Iridotsyklit), which is clinically manifested by pain, photophobia, hazy vision; 2) the bones, especially phalanxes of fingers and toes that are revealed mainly radiographically; 3) the Central and peripheral nervous system; 4) heart, liver, glands of internal secretion and other
Pathognomonic for sarcoidosis clinical symptom no; diagnostics complex.
An important diagnostic criteria sarcoidosis are tuberculin skin test, by type of reaction Pirke: positive reaction by 1% and 5% tuberculin almost impossible sarcoidosis. Specify the diagnosis of sarcoidosis clinical-roentgenological examinations and dynamic observation of patients.
The prognosis isgenerally favorable, but in some cases serious. In far comes pneumosclerosis death can occur from respiratory failure or heart failure. Damage to the eyes can cause blindness.
Effective method of treatment - long appointment of corticosteroid drugs. The patient must be under medical supervision.