Sepsis

  • Types of sepsis
  • Treatment and prevention of sepsis
  • Sepsis in children
  • Sepsis (synonym General purulent infection) infectious process caused by different pathogens, characterized by the appearance in blood viable micro-organisms, extending generally from local inflammatory focus, and proceeding on a background of significant changes in the reactivity of the organism.
    Sepsis often called stafilo - or streptococci, but there is sepsis and other etiology: anaerobic, anthrax and other sepsis caused not only by the properties of the pathogen as violations of resistibility of an organism is the failure of his defenses. Depending on the degree of reactivity of the organism even some common infectious diseases can cause sepsis (e.g. septic form of scarlet fever).
    In clinical-anatomical features distinguish two main forms of sepsis: septicaemia (or sepsis without metastasis) and septicopyemia (or sepsis with metastasis).
    Septicaemia ("ghilarovi") is the most severe, rapidly progressive form of sepsis. It is characterized by the multiplication of microorganisms in the patient's blood. The disease is characterized by a very severe condition of the patient, the expressed intoxication, toxic changes of internal organs, rapidly increasing analizarea. This form usually develops when a strep infection and is associated with particularly significant violations of resistibility of the organism.
    For septicemia characteristic is a fast progressing deterioration of the patient, in some cases, absolutely inadequate to the gravity of the injury or purulent process. Clinically septicaemia is manifested pronounced intoxication: constant intense headaches, irritability, insomnia, often oppressed General condition, with loss of consciousness. Fixed characteristics are rising temperatures up to 39-40°, followed drenching sweat, terrific fever, tachycardia 120-140 beats per minute. Attention is drawn to point bleeding of the skin. The pulse is weak filling, there is a decrease in blood pressure, muting heart sounds. In the peripheral blood falls the number of erythrocytes, hemoglobin, accelerated ROHE, the number of leukocytes. In the urine protein and formed blood elements.
    About violation of the liver shows yellowness of the sclera of the eye, skin, enlarged painful liver. An enlarged spleen. No appetite, marked persistent diarrhea, nausea, vomiting. When blood cultures, especially once, not always discovered bacteria.
    For septicemia is particularly acute in cases of infection of wounds; secondary infection causes less formidable for. Forecast in septicemia bad.
    To differentiate septicaemia more often from severe purulent-resorptive fever (see), which develops as a result of absorption of toxic products from any source of infection. To distinguish sepsis helps set with bandaging and inspection wounds mismatch of gravity of the General condition of the patient with the local changes in the wound, which is covered with dull, dry granulation with scarce discharge, often rotten character (Fig. 5). In other cases, the detection is possible by taking into account the effectiveness of surgery at the source of infection - wide opening of the suppurative focus in resorptive fever quickly improves the condition of the patient, something that does not happen in sepsis.

    sepsis
    Fig. 1. Septic endometritis. Fig. 2. Nanaimoin heart attacks easy. Fig. 3. Septic wound. Fig. 4. Empyema with multiple sclerosis visceral and parietal leaves.