Sequestration, sequestration

Sequestration is dead area of bone, muscle, tendon or body who have lost touch with living tissues. Sequestration is the process of separation of sequestration.
Sequestration is formed as a result of bacterial toxins in acute purulent process or as a result of thrombosis of vessels. Correct treatment in the early stages of the disease, particularly aimed antibiotic therapy, can prevent or limit the tissue necrosis and education of curtailment. Small curtailment may melt under the action of enzymes of pus or the local application of proteolytic enzymes (trypsin, hemoctin, chymotrypsin and others). Major curtailment lead to the transition suppuration chronic, often with the formation of external fistula (see). Small curtailment may be released independently through fistula, a major curtailment require surgical intervention (see Sequestrectomy). Without the removal of the sequester chronic purulent process cannot be cured.
Most often sequestered bone in haematogenic osteomyelitis (see); and the curtailment can be the size from a few millimeters to the entire femoral diaphysis or humerus. Also often formed curtailment of lung tissue when gangrene and lung abscess, curtailment of the pancreas with acute destructive pancreatitis.