Seroprotection (serum prevention, passive immunization) - early use of immune sera, normal or immune gamma globulin or serum healthy adults for the prevention of infectious diseases.
The best effect is achieved at the earliest use of gamma globulin or serum from possible infection.
Unlike vaccination (see), with seroprevalance in the body are introduced serum (see) with antibodies and, therefore, the body almost immediately becomes more or less resistant to a specific infection. In some cases seroprevalencia, not preventing the disease, leads to decrease its severity, frequency of complications and mortality.
However, seroprevalencia provides passive immunity only within 25-30 days. The introduction of serum obtained from the blood of animals, can cause serum sickness (see) and is threatening complication, as anaphylactic shock (see Anaphylaxis). To prevent serum sickness in all cases the serum is administered by Besedke in two stages: first 1.5 - 2 ml, and in 1.5-2 hours the entire dose, or better, for the first time - 0.1 ml 30 min-0.2 ml and after 1 hour the whole dose. More effectively with the aim of seroprotection to introduce gamma globulin (see).
Seroprotection conduct against tetanus, anaerobic infections, diphtheria, anthrax, plague, botulism, and other diseases. When the number of infectious diseases simultaneously with serum drugs when seroprevelance use and other means: antibiotics when plague, with tetanus toxoid, etc.
Cm. also Serotherapy.