Siena syndrome

Siena syndrome - a set of symptoms that result hypofunction of the anterior lobe of the pituitary gland (hypopituitarism). Syndrome Siena manifested amenorrhea, agalactia, hypoglycemia, hypotonia, cachexia; patients apathetic, they disappear sexual desire (libido), drop out pubic hair and axillary cavities. Observed among young women of childbearing age (25-29 years) after birth, complicated by large blood loss, generalized infection (sepsis), thrombosis and subsequent necrosis of the anterior pituitary.
For several years after birth with the syndrome of Siena menstruation are very rare - one or two times during the year. Despite infrequent menstruation, perhaps a pregnancy, if the injured person is a minor part of the pituitary gland.
Treatment: apply (by prescription) drugs cortisone, tireoidin, testosterone. The positive results obtained from the use of combinations of cortisone and tireoidina.
Prevention: compulsory hospitalization of pregnant women; at the big loss of blood in childbirth - massive (sufficient) blood transfusion; infection prevention; women after the birth of pathological need a long time to be under surveillance antenatal clinic.

Siena syndrome (N. L. Sheehan) is a syndrome characterized by several symptoms of hypopituitarism: amenorrhea, agalactia, hypoglycemia, hypotonia, cachexia. Occurs in women after childbirth, complicated by large blood loss, generalized infection (sepsis), thrombosis and subsequent necrosis of the anterior pituitary. Chihana the syndrome occurs commonly in young women of childbearing age, when it notes the low level of sugar in the blood, 17-oxycorticosteroids, 17-ketosteroids, especially fraction of DHEA, estrogen, and gonadotropins in the urine. Not always the syndrome manifests itself in the classical form, some of the cases occur atypical. For several years after birth, there remains a weak menstrual function, menstruation are very rare, one or two times during the year. Despite infrequent menstruation may pregnancy in cases where there is insignificant necrotization the anterior pituitary. Chechen notes that even at extensive necrosis of the anterior pituitary gland remaining tissue is still able to produce a number of gonadotropin. Therefore, the presence of rare menstruations not be considered as a favourable sign.
Treatment: used drugs cortisone, tireoidin, testosterone. The positive results obtained from the use of combinations of cortisone and tireoidina.
Prevention. Compulsory hospitalization of pregnant women; at the big loss of blood in childbirth - massive transfusion; prevention of infections. Long-term observation in consultation women after the birth of pathological.