Symptoms and course of gastric cancer

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Destruction of tumor, causing the development of purulent and putrefactive processes, leading to thrombosis and arrosee feeding vessels, resulting starts bleeding. Bleeding is usually small. Often the blood can be detected in Calais only when its chemical research (reaction of yens Gregersen collection). However, once begun, bleeding continues steadily in view of the ongoing disintegration of a tumour. So for gastric cancer is typically not a one-time detection and constant presence in the stool occult blood. More heavy bleeding that cause bloody vomiting and tarry stools, have to meet seldom. It happens when engaging in destructive process vessels supplying the gastric wall, the calibre of which is more significant. Such bleeding in some cases can lead to heavy blood loss and requires the use of the most energetic treatment.
Permanent loss of even small amounts of blood gradually leads to severe hypochromic anemia with a very large reduction of hemoglobin (up to 33 g/l or less) and erythrocytes (up to 1.5 x 1012 /l or less) and to a significant gipoproteinemii.
Such changes in the peripheral blood of normal in the long course of the cancer, not leading to a violation of patency of the digestive tract. If the patient has a narrowing of the input or output of the Department of the stomach, the coming year because of the lack of input in the body fluids of his dehydration leads to thickening of the blood, and then part of it may be little different from the usual.
Violation of patency of the digestive tract quickly leads to progressive depletion of the patient. The weight of his body has been steadily decreasing. Sometimes within 1-2 months - by 20-30 kg and more. However, no less depletion may occur with full patency of the digestive tract. The reason for this may be a constant intoxication of the organism by decay of the tumor and the development of septic phenomena, disorders of the digestive ability of the stomach, pancreas, liver by drawing them into a painful process, lack of appetite, an aversion to food, chronic malnutrition because of the painful sensations that occur after meals, and so on, thereby increasing reduce body weight, disappears subcutaneous fat layer, the skin is flabby, turgor it decreases so that gathered a fold of it has not spread and becomes grayish-white or slightly yellowish color. The latter may depend on the suction streamed blood, and from the involvement in the process and the liver ducts.
Also disappears fibre and on the face of the patient. His features sharpened temporal region and cheeks become hollow, begin to contributes cheekbones. The lips, the tip of the nose, the nails often cyanotic. On the cheeks sometimes there is a slight feverish glow. The combination of the above characteristics to create a picture called a cancer cachexia.
By S. A. Holdin (1970) frequency of symptoms of stomach cancer in patients who were treated at the research Institute of Oncology. N. N. Petrova, was the following: pain in the epigastric region - 86%, reduction of body weight is 78%, belching -68%, vomiting -48%, asymptomatic
over - 2,2%. According to the Mayo clinic, 11000 patients first complaints dyspeptic symptoms were at 52%, signs of ulcer - 27,8%, depletion - 8%, bleeding - 1,3%, other signs 10,9% [W. Walters et al., 1942].