Toxic syndrome

Toxic syndrome in children, severe General non-specific reaction of an organism of the child early (infant and toddler age on the introduction of microbial toxins and viruses, as well as on the introduction of the food, are not relevant in qualitative and quantitative terms, this condition of the body.
Toxic syndrome may occur for a variety of diseases, the most frequent diseases infectious nature - dysentery, Coelenterata, staphylococcal enteritis, the Salmonella infectionsand diseases that are not associated with primary infection,dyspepsia (see), hereditary diseases of metabolism. With toxemia often occur respiratory viral infection, pneumonia, otitis and other diseases in young children.
In the basis of the toxic syndrome lies serverelement reaction to the irritation of the nervous system, its vegetative departments, bacterial toxins, viruses, tissue decay products. Response this is not adequate stimulus and is characterized as giperergicakie. In the neurohumoral violations come pathological changes in the organism: spasm and expansion of blood vessels, increases the porosity of their cell membranes occur diapedetic micro - and macroglobuline (see Diabetes), disturbed intracellular salt balance. Toxic syndrome may occur with dehydration (with exicosis) and without dehydration of the child.
Toxicosis without dehydration in the form of complex nerverending reactions developing in a result of stimulation of the Central nervous system, called neurotoxicosis. The neurotoxicosis more likely to occur in children who have family trauma or suffering from congenital encephalopathy, and in the beginning many of acute infectious diseases. Clinically neurotoxicosis characterized by severe condition of the patient, increased body temperature, anxiety, impaired consciousness, seizure twitching facial muscles, involuntary movements of the arms and legs, klonico-tonic spasms (see), meningoencephalitis symptoms. Breathing is often uneven. Cardiovascular abnormalities occur as tachycardia, a flicker of pulse, enlargement of the heart, unstable blood pressure, tone deaf heart. When neurotoxicosis along with General symptoms may be observed violations of the gastrointestinal tract and manifest failure of the liver, kidneys and adrenal glands.
The severity of the clinical picture toxicity with exicosis connected with a huge loss of water and salt.
The child can sharply grow intoxication, violated hemodynamics and to be a shock. This clinically note motionless face, frozen (without blinking), staring at the space eyes, deep-sunken eyes, zapasy a large fontanel. The child is in suporosna or coma (see Consciousness disorders). The relative border of the heart is reduced, pulse frequency, heart sounds deaf. May develop acute heart failure. Radiograph shows swelling of lung tissue.
The rapid development of toxemia with exicosis accompanied by vomiting, diarrhea. Chair frequent, cal liquid, watery; fecal allocated jet admixture separated epithelium gives them a whitish appearance. Developed dehydration is accompanied by fever, a big weight loss. The turgor of tissues rapidly reduced, the skin becomes grayish-greenish color, dry, wrinkled, easy going in the folds. Urination rare, can be oliguria. With the progression of the disease are observed low or high tone muscle twitching facial muscles, messy automatic movement, limbs become cyanotic and cold.
Forecast serious, possibly fatal.

  • Treatment of toxic syndrome