Vaccination disease

Vaccination disease - a disease that occurs as a result of inoculation into skin of the person of the virus ospowiki, occurring usually in the form of light. Develops in 3-4 days after vaccination, when around scarificatoare skin appears inflammatory focus on a spot. Spot turns into papules, then in multi-vesicles - bubble with a red border on the periphery and indrawing in the center, and on 7-8-th day in pustules (Fig. ). At the same time appear fever (temperature 37-39 degrees), headache, weakness, anxiety, nausea or vomiting, particularly limited soy and appetite. Priuchayut the regional lymph nodes. In the blood, leukocytosis. From the 11th - 12th day of the pustule shrinks, becomes a crust, after the falling away of which remains flat scar. The disease is usually easy and requires no special treatment.
When hematogenous spread of vaccinia virus develops vaccination with severe sepsis local and systemic manifestations. Vaccination, the disease is sometimes complicated by the generalized rash allergic origin, skarlatinopodobnoy, Korepanova, urticarnae and exudative nature. Less rash happens hemorrhagic. In young children and adults at non-observance of rules of hygiene possible perenivka vaccine on other areas of the skin (see Vaccine rash).
Severe forms of vaccination of the disease and its complications usually develop in people with no immunity to smallpox and for violations of the rules of asepsis. The vaccination complications of the disease include meningoencephalitis, abscesses, phlegmons. When complications, and for accession by other infection apply antibiotics (penicillin adults : 200 000 IU 5-6 times a day, children under 50 000-100 000 IU 4-5 times a day for 5 to 7 days intramuscularly; tetracycline and biomitsin adults : 200 000 IU 3-4 times a day for children up to 3 years 25 000 IU per 1 kg of body weight per day, older 300 000-600 000 IU a day 4-5 methods for 6-8 days), antipyretic (acetylsalicylic acid 0.25 g 3 - 4 times a day, amidopyrine to 0.25 g 3-4 times a day), and antihistamines (diphenhydramine 0.03 g 2 times a day, pipolfen 0.025 g 2-3 times a day after meals), vitamins (a, C, b and rutin) in General therapeutic doses of gamma globulin (from 0.3 to 0.35 ml per 1 kg of body weight).

Vaccination disease: successive stages of development of the vaccination process on the skin. And-with the primary vaccination: 1 - the fourth day; 2 - sixth; 3 - the twelfth; 4 - fourteenth; 5 - twenties; 6 - the twenty-first day. B - for revaccination: 1 - the third day; 2 - sixth; 3 - ninth; 4 - tenth; 5 - thirteenth; 6 - the fourteenth day.