Vitiligo

vitiligoVitiligo (synonym PES) is one of the forms of dyschromia skin (see), manifested depigmentirovannah spots of various shape and size (see figure).
The development of vitiligo is associated with neuroendocrine disorders, mainly by changing the function of the thyroid gland, rarely of the adrenal, pituitary , and sex glands. A greater role for the various violations of the neurovascular apparatus of the skin. The spots that occur more often in the open areas of skin, sharply defined and tend to peripheral growth, surrounded by a zone of hyperpigmentation, gradually turning into the normal color of the skin. Sometimes depigmented spots, together, form an extensive lesions of the skin. Subjective sensations there. The onset of the disease in most cases gradual.
Most expressed vitiligo in the summer due to increased skin pigmentation on the edge depigmentirovannah areas. Hair in areas of depigmentation also lose their color, but may not be changed. Clinical type of vitiligo is a so-called nevus of Cetona characterized by the appearance oval or round depigmentirovannah spots around pigmented nevi.
Extremely rare is the combination of vitiligo with severe acute uveitis (see), premature graying of hair, total hair loss, deafness and glaucoma (syndrome Vogt - Koyanagi). For vitiligo long.
Treatment: inside appoint beroksan, ammifurin (tablets of 0.02 g), local - lubrication foci 1-2% solution of ammifurin with later (in 1-2 hours) exposure to the ultraviolet rays (10 times). 20-30 days the treatment can be repeated. Treatment RIP should be carefully: possible development bullous dermatitis on places of exposure, and therefore exposure to the sun during treatment patients is contraindicated.
Cm. also Leucoderma.