Astringents - substances which when applied to mucous membranes or broken skin cause partial collapse of proteins that are in mucus or tissue fluid, and form a film that protects the nerves from exposure to irritants; this reduces the pain. The surface layer of the cytoplasm of cells under the influence of binders compacted cells decrease secretion from their surface is becoming less abundant.
Small vessels are narrowed due to seal their walls and in the result of compression of the surrounding tissues. Limiting the swelling and secretion, causing vasoconstriction and decrease pain, binders have anti-inflammatory effect.
Astringent properties are substances of plant origin: tannin (see), tealby (see), drugs oak bark, grass zveroboja, leaves of sage and others, some salts and oxides of metals - lead acetate, alum (see), kseroforma (see) and other
Astringents are prescribed for inflammatory diseases of the skin and mucous membranes, as well as in cases when it is necessary to protect sensitive nerve endings from exposure to irritants: when eczema, acute dermatitis, burns, ulcers, fractures, bedsores, stomatitis, gingivitis, quinsy, gastritis, stomach ulcer, ulcerative colitis, and enteritis, diarrhea.