The influence of sex hormones on the body of women in different age periods

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The secretion of androgens yellow body slightly greater than follikulina phase of the cycle. If not happened fertilization, the yellow body is in involution and the secretion of hormones by the ovary is sharply reduced. Comes menstruation. Endometrial under the influence of estrogen and progesterone happen cyclical changes in glands and stroma, the vessels of the endometrium. Under the influence of ovarian hormones change the uterine tone, peristalsis of the fallopian tubes, state isthmic Department of the uterus.
In follikulina phase under the action of estrogen is growth of functional layer of the endometrium: it increased the number and volume glands. Endometrial stroma is loosened, the number of connective tissue cells. In the second phase of the cycle under the influence of progesterone endometrial cancer begin to produce a secret, containing a large amount of glycogen and glycoproteins. Gaps glands expand considerably. Increase in volume and cell endometrial stroma, turning into large polygonal cells with a large kernel. Luteal phase of the cycle functional layer of the endometrium reaches the greatest thickness, increasing in comparison with follikulina phase about 10 times. Sharp decrease of secretion of progesterone and estrogen leads to the rejection of the functional layer of the endometrium, which is manifested in the onset of menstruation.
Under the influence of estrogen in predoperatinom period there is an increase of contractile activity of the uterus and fallopian tubes. It promotes sperm towards the fallopian tubes, where fertilization.
Under the influence of progesterone during the luteal phase of the cycle reduces the ability Oxytocics Oxytocics; isthmic Department of the uterus, advanced in the first phase of the cycle to 0.3 cm, sharply tapering luteal phase. Deficiency of the hormone yellow body in the early stages of pregnancy may be a cause of premature interruption.
Under the influence of the hormones oestrogen happens proliferation and then, to the period of ovulation, keratinization part cells of the vaginal epithelium, then in phase yellow body appear intermediate cells with "wrapped" edges (due to the effect of progesterone on vaginal epithelium). In the cervical canal under the influence of the hormones oestrogen appears mucus. The number gradually increases and reaches its maximum to the phase of the ovulatory phase of the yellow body slime disappears. Such changes occur monthly.
In the period premenopause almost ends reproductive cycle: decreases the secretion of estrogen, stops ovulation. Yellow body develops not enough, it never formed. Increases secretion of the gonadotropic hormones. Thus, to premenopausal changes in hormonal homeostasis. In healthy women it is characterized by reduced and "monotonous" the secretion of estrogen, the lack of progesterone, a decrease androgen levels, increased secretion of the gonadotropic hormones. These changes in hormonal homeostasis cause of the above changes in the reproductive system and the organism as a whole.
We pay special attention to changes in hormonal homeostasis in connection with the fact that they can cause many of the pathological processes that occur most frequently in the period of aging. The nature of hormonal changes in menopause is also essential for the choice of therapy, so that the dosage prescribed hormonal drugs compliance with the norms of the age of homeostasis.