Intrauterine sensitization

In 1928 Ratner [40] found that sensitization to cow milk proteins in Guinea pigs developed in utero. The author made an assumption about the possibility of such phenomena and people. Apparently, this assumption is true in some cases, when the child develops an explicit allergic reaction after the first contact with food antigens, usually with antigens of cow's milk. If you agree with the viewpoint that a transition antigens from the mother to the fetus, such immune response will not cause surprise, since the ability to synthesize antibodies occurs already at 8-12-week fetus [41-43]. The formation of specific antibodies to cow milk proteins were found in premature infants born at 35 weeks pregnant [11, 12]. It also describes the occurrence of acute hypersensitive reactions after the first intake of cow's milk in children who are breastfed [9]. In one study, the authors admit the possibility of fetal sensitization in 5 children with eczema, which developed after the first feeding cow's milk (3 children) and infant soy formula (2 children); the title of hemagglutinin to lactalbumin or to protein soy in the amniotic fluid in these children was raised [44]. In our practice there were cases of occurrence of babies, breastfeeding, Allergy symptoms to those foods that the mother consumed in excessive quantities during pregnancy; similar data was obtained Gerrard [45]. The described case of positive PACT in the study of serum blood from the umbilical cord to the antigens of cow's milk [46]. According to our data, in some cases serum blood from the umbilical cord contain the reagents for the protein of cow's milk.