Weigle reaction

Weigle reaction - macroscopic response agglutination, previously used for the diagnosis of typhus. Detected on the 4-6th day of illness and reaches its maximum at the fall of the temperature and the height of the title corresponds to the severity of the disease. To the serum of patients add antigenisolated from ricketsi of Prowazeki, cultivated in the intestines of infected fleas. The reaction of Weigle positive when dark sediment on the bottom of the tube with a clear liquid over it; if negative reaction of Weigle liquid remains murky. Currently, the reaction of Weigle not apply Cm. also typhus, diagnosis.