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Issues of hypervitaminosis D in children devoted a lot of research, but it still wasn't generalizing works. With this in mind, we have included in this book for information about the main reasons of hypervitaminosis D, distribution, pathogenesis, and clinics.
The rapid progress in biochemistry and other Sciences has allowed a deeper study of metabolic shifts, in particular tissue processes arising from this disease, which is of great importance for the correct interpretation of the basic clinical manifestations, and treatment of disease.
In recent years in the fight to reduce child morbidity and mortality, for the further improvement of children much attention is paid to the systematic prevention, early detection and complete treatment of rickets. However, the fascination with the preparations of vitamin D without proper conduct of other prevention and care activities have led to increased hypervitaminosis D among children. You should consider the possibility of development D-vitamin intoxication from the use of conventional therapeutic and prophylactic doses as a result of increased individual sensitivity to this drug. The difficulty of identifying the initial symptoms of hypervitaminosis D, with a predominance of common features often leads to late detection true pathology.
Diagnosis of this disease should be comprehensive. The great value has carefully collected and analyzed the history indicating the use of vitamin D. the earliest clinical symptoms are irritability, lethargy, lethargy, insomnia, sweating, indicating the involvement in the pathological process of the nervous system. In addition, the child shows decreased appetite, up to the full anorexia, vomiting, constipation, diarrhea, or an unstable chair. Simultaneously observed violations from different organs and systems, especially the kidney, heart and other
Great diagnostic value are the results of laboratory research. In particular, to confirm the diagnosis of hypervitaminosis D it is important to know the content of Ca in the blood, to undertake a study of urine on Sulkowice. Technically trial of Sulkowice quite simple and at the same time allows to reveal the degree of calciuria. In addition, when D-vitamin toxicity is observed hypophosphatemia, hypomagnesemia, gipernatriemia, dysproteinemia, and often hypercholesterolemia. The essential help in the diagnosis has x-ray study of the bones.
At the same time great attention to studying the causes, clinic, classification, differential diagnosis, as well as the principles of treatment and prevention of this disease in children.
There is still no common classification for gipervitaminoza D. Our observations have shown the feasibility of using the new classification with the release of the severity of the disease (mild, moderate, severe), the period of the disease and its course (acute, chronic). Depending on the predominant lesion of various organs desirable to allocate forms of hypervitaminosis D - renal, cardiovascular, gastrointestinal, nervous and other
This classification makes it possible to correctly interpret the clinical manifestations of disease, and take to choose the most rational methods of therapy. The effectiveness of treatment D-vitamin intoxication depends on the timely diagnosis of the disease. Even if you suspect the hypervitaminosis D should be discontinued immediately vitamin D and preparations Ca. From a child's diet excludes products with high content of Ca (cheese, cow's milk).