Bile pigments

Bile pigments - cleavage products heme hemoglobin that is released with jelchew and giving it a characteristic color.
In the liver, the formation of bilirubin (see), which is in the form of bilirubinuria (and partially free bilirubin) is transferred together with bile in the gallbladder. Subsequent transformations occur mainly in the gut by the action of intestinal microflora and oxygen. One day a man 0,5 - 1 g bile pigments, and reverse absorption from the intestines to the blood undergoes a small part of them. When liver disease in blood serum increases the content of bilirubin (free or bound), which is found reaction van-den-Berg with special detraction. Free bilirubin is detectable gallbladder appearance of pink or red colour (direct reaction)connected only after the destruction of glucuronid connection with alcohol added to the sample (indirect reaction). Direct reaction occurs when the blockage of the bile ducts and liver diseases, indirect inherent as the normal condition of the body, and in the case of hemolytic jaundice. Sample Huppert - Salkovsky can detect bilirubin in urine sediment by adding acidified alcohol and a few drops of chloroform; thus there is a yellow color. For qualitative detection of bile pigments use the sample Gmelin (see Gmelin test), a sample of Rosenbach (after filtration of liquids containing bile pigments, on a paper filter, put a drop of concentrated nitric acid mixed with nitrous acid, on the filter, a number of colored concentric rings), and a sample of Rosina in urine (when layering 1% iodine alcohol solution on the border between liquids appears green ring). Cm. also Hemoglobin, Stercobilin, the Urobilin.