Fatty liver

Fatty liver (steatosis of the liver") is characterized by the appearance of fat droplets in the hepatocyte cytoplasm and coppersky cells. Droplet size depends on the speed and duration of fat accumulation. Oil droplets are in normal color view of bright balloons, Sudan III-IV they are colored orange-red color black Sudan - black. Thaler (1962) distinguishes between three degrees of obesity: disseminated - fatty infiltration of individual cells; zonal, covering whole areas, sometimes several slices, and diffuse - obesity throughout the parenchyma of the liver.
Filled with hepatic fat cells increase in size, the kernel is shifted to the periphery. Fat drops a few cells may merge to form fatty cysts with multiple cores on the periphery (Fig. 53). Fatty degeneration may long remain stable. Possible and its evolution to cirrhosis. In the basis of fatty infiltration is a violation of the process of phosphorylation of neutral fats and their transformation into functionally active phospholipids. Phospholipids can be detected as fat as a result of disintegration of phospholipid complexes. It is necessary to consider that the appearance of fat in the liver possible in physiological conditions as a result of increased inflow of fat from the intestinal tract. In this case, obesity does not reach large degrees and is of a transient nature.

Fig. 53. Fatty degeneration of liver cells. Explanation in the text.